SpONGE: spontaneous organization of numerous-layer generation by electrospray.
Angew Chem Int Ed Engl
; 54(26): 7587-91, 2015 Jun 22.
Article
in En
| MEDLINE
| ID: mdl-25958994
ABSTRACT
Advanced technologies that can mimic hierarchical architectures found in nature can provide pivotal clues for elucidating numerous biological mechanisms. Herein, a novel technology, spontaneous organization of numerous-layer generation by electrospray (SpONGE), was developed to create self-assembled and multilayered fibrous structures. The simple inclusion of salts in a polymer solution prior to electrospraying was key to mediating the structural versatilities of the fibrous structures. The SpONGE matrix demonstrated great potential as a crucial building block capable of inducing sequential, localized drug delivery or orchestrating cellular distribution inâ
vivo, thereby expanding its scope of use to cover a variety of biomedical applications.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Angew Chem Int Ed Engl
Year:
2015
Document type:
Article