[Central hemodynamics and kidney function in women with pre-eclampsia]. / Sustoianie na tsentralnata khemodinamika i bubrechnata funktsiia pri zheni s preeklampsiia.

ABSTRACT

A radionuclide method with quickly disintegrating 99MTC labelled human albumin and DTPA in a volume of 0.3-0.5 ml and activity of 37 mVk with two consecutive examinations of central and renal hemodynamics was used in 91 pregnant women with preeclampsia and pyelonephritis. Marked hypovolemia was found in all groups of investigated women with preeclampsia with the exception of the group of women with pyelonephritis. There was also difference in arterial pressure in women with preeclampsia I degree and pyelonephritis, which was statistically significant with advancement of gravity and duration of the disease. The investigation of the functional state of kidneys and blood flow showed a tendency to slowing both in the arterial and venous circulation in women with pre-eclampsia of pregnancy. In the pregnant women of this group and the women with pyelonephritis there was asymmetry in the curves of the blood flow as well as in the temporary indices of renal filtration, which were increases two-folds in comparison with the normal values. They were mostly manifested on the side of the involvement in women with pyelonephritis. Irradiation loading was 0.212 mZv of both examinations and was ten times less than that of x-ray pelvimetry.