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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.
Patel, Avinash; Lee, Hyun O; Jawerth, Louise; Maharana, Shovamayee; Jahnel, Marcus; Hein, Marco Y; Stoynov, Stoyno; Mahamid, Julia; Saha, Shambaditya; Franzmann, Titus M; Pozniakovski, Andrej; Poser, Ina; Maghelli, Nicola; Royer, Loic A; Weigert, Martin; Myers, Eugene W; Grill, Stephan; Drechsel, David; Hyman, Anthony A; Alberti, Simon.
Affiliation
  • Patel A; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Lee HO; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Jawerth L; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany; Max Planck Institute for the Physics of Complex Systems, 01187 Dresden, Germany.
  • Maharana S; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Jahnel M; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Hein MY; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
  • Stoynov S; Institute of Molecular Biology, Bulgarian Academy of Sciences, 21, G. Bontchev Str., Sofia 1113, Bulgaria.
  • Mahamid J; Department of Molecular Structural Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.
  • Saha S; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Franzmann TM; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Pozniakovski A; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Poser I; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Maghelli N; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Royer LA; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Weigert M; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Myers EW; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Grill S; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Drechsel D; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Hyman AA; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany. Electronic address: hyman@mpi-cbg.de.
  • Alberti S; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany. Electronic address: alberti@mpi-cbg.de.
Cell ; 162(5): 1066-77, 2015 Aug 27.
Article in En | MEDLINE | ID: mdl-26317470
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / RNA-Binding Protein FUS / Amyotrophic Lateral Sclerosis / Mutation Limits: Humans Language: En Journal: Cell Year: 2015 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / RNA-Binding Protein FUS / Amyotrophic Lateral Sclerosis / Mutation Limits: Humans Language: En Journal: Cell Year: 2015 Document type: Article Affiliation country: Country of publication: