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Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists.
Fauber, Benjamin P; Gobbi, Alberto; Savy, Pascal; Burton, Brenda; Deng, Yuzhong; Everett, Christine; La, Hank; Johnson, Adam R; Lockey, Peter; Norman, Maxine; Wong, Harvey.
Affiliation
  • Fauber BP; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: Fauber.Benjamin@gene.com.
  • Gobbi A; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Savy P; Argenta, Discovery Services, Charles River, Units 7-9 Spire Green Centre, Flex Meadow, Harlow, Essex CM19 5TR, UK.
  • Burton B; Argenta, Discovery Services, Charles River, Units 7-9 Spire Green Centre, Flex Meadow, Harlow, Essex CM19 5TR, UK.
  • Deng Y; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Everett C; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • La H; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Johnson AR; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Lockey P; Argenta, Discovery Services, Charles River, Units 7-9 Spire Green Centre, Flex Meadow, Harlow, Essex CM19 5TR, UK.
  • Norman M; Argenta, Discovery Services, Charles River, Units 7-9 Spire Green Centre, Flex Meadow, Harlow, Essex CM19 5TR, UK.
  • Wong H; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
Bioorg Med Chem Lett ; 25(19): 4109-13, 2015 Oct 01.
Article in En | MEDLINE | ID: mdl-26321361
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Drug Inverse Agonism / Nuclear Receptor Subfamily 1, Group F, Member 3 Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Drug Inverse Agonism / Nuclear Receptor Subfamily 1, Group F, Member 3 Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2015 Document type: Article Country of publication: