Characteristics and functions of lipid droplets and associated proteins in enterocytes.
Exp Cell Res
; 340(2): 172-9, 2016 Jan 15.
Article
in En
| MEDLINE
| ID: mdl-26431584
ABSTRACT
Cytosolic lipid droplets (LDs) are observed in enterocytes of jejunum during lipid absorption. One important function of the intestine is to secrete chylomicrons, which provide dietary lipids throughout the body, from digested lipids in meals. The current hypothesis is that cytosolic LDs in enterocytes constitute a transient pool of stored lipids that provides lipids during interprandial period while lowering chylomicron production during the post-prandial phase. This smoothens the magnitude of peaks of hypertriglyceridemia. Here, we review the composition and functions of lipids and associated proteins of enterocyte LDs, the known physiological functions of LDs as well as the role of LDs in pathological processes in the context of the intestine.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Biological Transport
/
Chylomicrons
/
Enterocytes
/
Lipid Metabolism
/
Lipid Droplets
Type of study:
Risk_factors_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Exp Cell Res
Year:
2016
Document type:
Article
Affiliation country: