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Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.
Hidvegi, Tunda; Stolz, Donna B; Alcorn, John F; Yousem, Samuel A; Wang, Jieru; Leme, Adriana S; Houghton, A McGarry; Hale, Pamela; Ewing, Michael; Cai, Houming; Garchar, Evelyn Akpadock; Pastore, Nunzia; Annunziata, Patrizia; Kaminski, Naftali; Pilewski, Joseph; Shapiro, Steven D; Pak, Stephen C; Silverman, Gary A; Brunetti-Pierri, Nicola; Perlmutter, David H.
Affiliation
  • Hidvegi T; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224.
  • Stolz DB; Cell Biology, and.
  • Alcorn JF; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224.
  • Yousem SA; Pathology University of Pittsburgh School of Medicine and.
  • Wang J; From the Departments of Pediatrics.
  • Leme AS; Medicine.
  • Houghton AM; Medicine.
  • Hale P; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224.
  • Ewing M; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224.
  • Cai H; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224.
  • Garchar EA; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224.
  • Pastore N; Department of Translational Medicine, Federico II University, Naples, Italy, 80138.
  • Annunziata P; Department of Translational Medicine, Federico II University, Naples, Italy, 80138.
  • Kaminski N; Medicine.
  • Pilewski J; Medicine.
  • Shapiro SD; Medicine.
  • Pak SC; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224.
  • Silverman GA; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224, Cell Biology, and.
  • Brunetti-Pierri N; Department of Translational Medicine, Federico II University, Naples, Italy, 80138 Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy, 80131, and.
  • Perlmutter DH; From the Departments of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224, Cell Biology, and david.perlmutter@chp.edu.
J Biol Chem ; 290(50): 29742-57, 2015 Dec 11.
Article in En | MEDLINE | ID: mdl-26494620
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Genetic Therapy / Alpha 1-Antitrypsin Deficiency Limits: Animals Language: En Journal: J Biol Chem Year: 2015 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Genetic Therapy / Alpha 1-Antitrypsin Deficiency Limits: Animals Language: En Journal: J Biol Chem Year: 2015 Document type: Article