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Cheminformatics-aided pharmacovigilance: application to Stevens-Johnson Syndrome.
Low, Yen S; Caster, Ola; Bergvall, Tomas; Fourches, Denis; Zang, Xiaoling; Norén, G Niklas; Rusyn, Ivan; Edwards, Ralph; Tropsha, Alexander.
Affiliation
  • Low YS; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA Department of Environmental Sciences and Engineering, Gillings School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
  • Caster O; Uppsala Monitoring Centre, Uppsala, Sweden Department of Computer and Systems Sciences, Stockholm University, Kista, Sweden.
  • Bergvall T; Uppsala Monitoring Centre, Uppsala, Sweden.
  • Fourches D; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA.
  • Zang X; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA.
  • Norén GN; Uppsala Monitoring Centre, Uppsala, Sweden Department of Mathematics, Stockholm University, Stockholm, Sweden.
  • Rusyn I; Department of Environmental Sciences and Engineering, Gillings School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
  • Edwards R; Uppsala Monitoring Centre, Uppsala, Sweden.
  • Tropsha A; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA alex_tropsha@unc.edu.
J Am Med Inform Assoc ; 23(5): 968-78, 2016 09.
Article in En | MEDLINE | ID: mdl-26499102
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stevens-Johnson Syndrome / Quantitative Structure-Activity Relationship / Drug-Related Side Effects and Adverse Reactions / Pharmacovigilance / Models, Chemical Type of study: Etiology_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: J Am Med Inform Assoc Journal subject: INFORMATICA MEDICA Year: 2016 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stevens-Johnson Syndrome / Quantitative Structure-Activity Relationship / Drug-Related Side Effects and Adverse Reactions / Pharmacovigilance / Models, Chemical Type of study: Etiology_studies / Prognostic_studies / Screening_studies Limits: Humans Language: En Journal: J Am Med Inform Assoc Journal subject: INFORMATICA MEDICA Year: 2016 Document type: Article Affiliation country: