[SHIFTS IN URINE PROTEIN PROFILE DURING DRY IMMERSION].
Aviakosm Ekolog Med
; 49(4): 15-9, 2015.
Article
in Ru
| MEDLINE
| ID: mdl-26554129
ABSTRACT
The study was aimed at tracking the proteomic profile of urine in 8 normal volunteers to 5-day dry immersion (DI). The proteome composition was determined by chromatography-mass spectrometry on high-efficient on-line liquid nano chromatograph Agilent 1100; complementary information about the protein spectra was obtained by dint of mass-spectrometer MaXis Impact 4G and hybrid mass-spectrometer LTQ-FT. Functional associations between proteins and biological functions were analyzed using computer system ANDCell (Associative Networks Discovery in Cells). A total of 256 proteins were identified; for 43 proteins difference in the detection rate during the baseline data collection and on DI day 4 exceeded 20%.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Proteinuria
/
Adaptation, Physiological
/
Weightlessness Simulation
/
Proteome
Limits:
Adult
/
Humans
/
Male
Language:
Ru
Journal:
Aviakosm Ekolog Med
Journal subject:
MEDICINA AEROESPACIAL
/
SAUDE AMBIENTAL
Year:
2015
Document type:
Article