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4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase.
Hanan, Emily J; Baumgardner, Matt; Bryan, Marian C; Chen, Yuan; Eigenbrot, Charles; Fan, Peter; Gu, Xiao-Hui; La, Hank; Malek, Shiva; Purkey, Hans E; Schaefer, Gabriele; Schmidt, Stephen; Sideris, Steve; Yen, Ivana; Yu, Christine; Heffron, Timothy P.
Affiliation
  • Hanan EJ; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Baumgardner M; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Bryan MC; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Chen Y; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Eigenbrot C; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Fan P; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Gu XH; Pharmaron Beijing CO. Ltd, No. 6 Taihe Road BDA, Beijing 100176, China.
  • La H; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Malek S; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Purkey HE; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Schaefer G; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Schmidt S; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Sideris S; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Yen I; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Yu C; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
  • Heffron TP; Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, United States.
Bioorg Med Chem Lett ; 26(2): 534-539, 2016 Jan 15.
Article in En | MEDLINE | ID: mdl-26639762
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Protein Kinase Inhibitors / ErbB Receptors / Furans / Indazoles Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Protein Kinase Inhibitors / ErbB Receptors / Furans / Indazoles Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2016 Document type: Article Affiliation country: