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Translational neurophysiological markers for activity of the metabotropic glutamate receptor (mGluR2) modulator JNJ-40411813: Sleep EEG correlates in rodents and healthy men.
Ahnaou, A; de Boer, P; Lavreysen, H; Huysmans, H; Sinha, V; Raeymaekers, L; Van De Casteele, T; Cid, J M; Van Nueten, L; Macdonald, G J; Kemp, J A; Drinkenburg, W H I M.
Affiliation
  • Ahnaou A; Dept. of Neuroscience Discovery, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium. Electronic address: aahnaou@its.jnj.com.
  • de Boer P; Neuroscience Experimental Medicine, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium.
  • Lavreysen H; Dept. of Neuroscience Discovery, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium.
  • Huysmans H; Dept. of Neuroscience Discovery, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium.
  • Sinha V; Clinical Pharmacology in Titusville, 1125 Trenton-Harbourton Road, Titusville, NJ, 08560 USA.
  • Raeymaekers L; Dept. of Neuroscience Discovery, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium.
  • Van De Casteele T; Nonclinical Statistics and Computing, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340 Beerse, Belgium.
  • Cid JM; Neuroscience Discovery, Toledo C/Jarama, 75, Spain.
  • Van Nueten L; Neuroscience Experimental Medicine, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium.
  • Macdonald GJ; Dept. of Neuroscience Discovery, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium.
  • Kemp JA; Dept. of Neuroscience Discovery, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium.
  • Drinkenburg WH; Dept. of Neuroscience Discovery, Janssen Research & Development, A Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340, Beerse, Belgium.
Neuropharmacology ; 103: 290-305, 2016 Apr.
Article in En | MEDLINE | ID: mdl-26686390
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Pyridones / Sleep / Cerebral Cortex / Circadian Rhythm / Receptors, Metabotropic Glutamate Type of study: Clinical_trials Limits: Adult / Animals / Humans / Male / Middle aged Language: En Journal: Neuropharmacology Year: 2016 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Pyridones / Sleep / Cerebral Cortex / Circadian Rhythm / Receptors, Metabotropic Glutamate Type of study: Clinical_trials Limits: Adult / Animals / Humans / Male / Middle aged Language: En Journal: Neuropharmacology Year: 2016 Document type: Article Country of publication: