The 5300-year-old Helicobacter pylori genome of the Iceman.
Science
; 351(6269): 162-165, 2016 Jan 08.
Article
in En
| MEDLINE
| ID: mdl-26744403
ABSTRACT
The stomach bacterium Helicobacter pylori is one of the most prevalent human pathogens. It has dispersed globally with its human host, resulting in a distinct phylogeographic pattern that can be used to reconstruct both recent and ancient human migrations. The extant European population of H. pylori is known to be a hybrid between Asian and African bacteria, but there exist different hypotheses about when and where the hybridization took place, reflecting the complex demographic history of Europeans. Here, we present a 5300-year-old H. pylori genome from a European Copper Age glacier mummy. The "Iceman" H. pylori is a nearly pure representative of the bacterial population of Asian origin that existed in Europe before hybridization, suggesting that the African population arrived in Europe within the past few thousand years.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stomach
/
Helicobacter pylori
/
Helicobacter Infections
/
Genome, Bacterial
/
Hybridization, Genetic
Limits:
Humans
Country/Region as subject:
Asia
/
Europa
Language:
En
Journal:
Science
Year:
2016
Document type:
Article
Affiliation country: