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Small molecules preventing GAPDH aggregation are therapeutically applicable in cell and rat models of oxidative stress.
Lazarev, Vladimir F; Nikotina, Alina D; Semenyuk, Pavel I; Evstafyeva, Diana B; Mikhaylova, Elena R; Muronetz, Vladimir I; Shevtsov, Maxim A; Tolkacheva, Anastasia V; Dobrodumov, Anatoly V; Shavarda, Alexey L; Guzhova, Irina V; Margulis, Boris A.
Affiliation
  • Lazarev VF; Institute of Cytology of Russian Academy of Sciences, Tikhoretsky pr., 4, 194064 St. Petersburg, Russia. Electronic address: vl.lazarev@gmail.com.
  • Nikotina AD; Institute of Cytology of Russian Academy of Sciences, Tikhoretsky pr., 4, 194064 St. Petersburg, Russia.
  • Semenyuk PI; Belozersky Institute of Physico-Chemical Biology of Moscow State University, 119992 Moscow, Russia.
  • Evstafyeva DB; Belozersky Institute of Physico-Chemical Biology of Moscow State University, 119992 Moscow, Russia.
  • Mikhaylova ER; Institute of Cytology of Russian Academy of Sciences, Tikhoretsky pr., 4, 194064 St. Petersburg, Russia.
  • Muronetz VI; Belozersky Institute of Physico-Chemical Biology of Moscow State University, 119992 Moscow, Russia.
  • Shevtsov MA; Institute of Cytology of Russian Academy of Sciences, Tikhoretsky pr., 4, 194064 St. Petersburg, Russia.
  • Tolkacheva AV; Institute of Cytology of Russian Academy of Sciences, Tikhoretsky pr., 4, 194064 St. Petersburg, Russia.
  • Dobrodumov AV; Institute of Macromolecular Compounds Russian Academy of Sciences, 199004 St. Petersburg, Russia.
  • Shavarda AL; Komarov Botanical Institute Russian Academy of Sciences, 197376 St. Petersburg, Russia.
  • Guzhova IV; Institute of Cytology of Russian Academy of Sciences, Tikhoretsky pr., 4, 194064 St. Petersburg, Russia.
  • Margulis BA; Institute of Cytology of Russian Academy of Sciences, Tikhoretsky pr., 4, 194064 St. Petersburg, Russia.
Free Radic Biol Med ; 92: 29-38, 2016 Mar.
Article in En | MEDLINE | ID: mdl-26748070
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholestanols / Oxidative Stress / Guanidine / Small Molecule Libraries / Protein Aggregation, Pathological / Glyceraldehyde-3-Phosphate Dehydrogenases Limits: Animals / Humans Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2016 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholestanols / Oxidative Stress / Guanidine / Small Molecule Libraries / Protein Aggregation, Pathological / Glyceraldehyde-3-Phosphate Dehydrogenases Limits: Animals / Humans Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2016 Document type: Article