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Healthcare-associated Crimean-Congo haemorrhagic fever in Turkey, 2002-2014: a multicentre retrospective cross-sectional study.
Leblebicioglu, H; Sunbul, M; Guner, R; Bodur, H; Bulut, C; Duygu, F; Elaldi, N; Cicek Senturk, G; Ozkurt, Z; Yilmaz, G; Fletcher, T E; Beeching, N J.
Affiliation
  • Leblebicioglu H; Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis University Medical School, Samsun, Turkey. Electronic address: hakanomu@yahoo.com.
  • Sunbul M; Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis University Medical School, Samsun, Turkey.
  • Guner R; Department of Infectious Diseases and Clinical Microbiology, Yildirim Beyazit University Medical School, Ankara, Turkey.
  • Bodur H; Department of Infectious Diseases and Clinical Microbiology, Ankara Numune Research and Training Hospital, Ankara, Turkey.
  • Bulut C; Department of Infectious Diseases and Clinical Microbiology, Ankara Research and Training Hospital, Ankara, Turkey.
  • Duygu F; Department of Infectious Diseases and Clinical Microbiology, Gaziosmanpasa University Medical School, Tokat, Turkey.
  • Elaldi N; Department of Infectious Diseases and Clinical Microbiology, Cumhuriyet University Medical School, Sivas, Turkey.
  • Cicek Senturk G; Department of Infectious Diseases and Clinical Microbiology, SB Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
  • Ozkurt Z; Department of Infectious Diseases and Clinical Microbiology, Ataturk University Medical School, Erzurum, Turkey.
  • Yilmaz G; Department of Infectious Diseases and Clinical Microbiology, Karadeniz Technical University Medical School, Erzurum, Turkey.
  • Fletcher TE; Department of Infectious Diseases and Clinical Microbiology, Ondokuz Mayis University Medical School, Samsun, Turkey; Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
  • Beeching NJ; Liverpool School of Tropical Medicine, Liverpool, United Kingdom; NIHR HPRU in Emerging and Zoonotic Infections, University of Liverpool, Liverpool, United Kingdom.
Clin Microbiol Infect ; 22(4): 387.e1-387.e4, 2016 Apr.
Article in En | MEDLINE | ID: mdl-26806137
ABSTRACT
Healthcare-related transmission of Crimean-Congo haemorrhagic fever (CCHF) is a well-recognized hazard. We report a multicentre retrospective cross-sectional study undertaken in Turkey in 2014 in nine hospitals, regional reference centres for CCHF, covering the years 2002 to 2014 inclusive. Data were systematically extracted from charts of all personnel with a reported health care injury/accident related to CCHF. Blood samples were tested for CCHF IgM/IgG by enzyme-linked immunosorbent assay and/or viral nucleic acid detection by PCR after the injury. Fifty-one healthcare-related exposures were identified. Twenty-five (49%) of 51 resulted in laboratory-confirmed infection, with a 16% (4/25) overall mortality. The main route of exposure was needlestick injury in 32/51 (62.7%). A potential benefit of post-exposure prophylaxis with ribavirin was identified.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemorrhagic Fever, Crimean / Occupational Diseases Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Humans Country/Region as subject: Asia Language: En Journal: Clin Microbiol Infect Journal subject: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Year: 2016 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemorrhagic Fever, Crimean / Occupational Diseases Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Humans Country/Region as subject: Asia Language: En Journal: Clin Microbiol Infect Journal subject: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Year: 2016 Document type: Article