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EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor.
Jia, Yong; Juarez, Jose; Li, Jie; Manuia, Mari; Niederst, Matthew J; Tompkins, Celin; Timple, Noelito; Vaillancourt, Mei-Ting; Pferdekamper, AnneMarie Culazzo; Lockerman, Elizabeth L; Li, Chun; Anderson, Jennifer; Costa, Carlotta; Liao, Debbie; Murphy, Eric; DiDonato, Michael; Bursulaya, Badry; Lelais, Gerald; Barretina, Jordi; McNeill, Matthew; Epple, Robert; Marsilje, Thomas H; Pathan, Nuzhat; Engelman, Jeffrey A; Michellys, Pierre-Yves; McNamara, Peter; Harris, Jennifer; Bender, Steven; Kasibhatla, Shailaja.
Affiliation
  • Jia Y; Genomics Institute of the Novartis Research Foundation, San Diego, California. yjia@gnf.org skasibhatla@gnf.org.
  • Juarez J; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Li J; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Manuia M; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Niederst MJ; Massachusetts General Hospital/Harvard Medical School Cancer Center, Charlestown, Massachusetts.
  • Tompkins C; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Timple N; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Vaillancourt MT; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Pferdekamper AC; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Lockerman EL; Massachusetts General Hospital/Harvard Medical School Cancer Center, Charlestown, Massachusetts.
  • Li C; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Anderson J; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Costa C; Massachusetts General Hospital/Harvard Medical School Cancer Center, Charlestown, Massachusetts.
  • Liao D; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Murphy E; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • DiDonato M; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Bursulaya B; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Lelais G; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Barretina J; Novartis Institute for Biomedical Research, Cambridge, Massachusetts.
  • McNeill M; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Epple R; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Marsilje TH; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Pathan N; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Engelman JA; Massachusetts General Hospital/Harvard Medical School Cancer Center, Charlestown, Massachusetts.
  • Michellys PY; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • McNamara P; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Harris J; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Bender S; Genomics Institute of the Novartis Research Foundation, San Diego, California.
  • Kasibhatla S; Genomics Institute of the Novartis Research Foundation, San Diego, California. yjia@gnf.org skasibhatla@gnf.org.
Cancer Res ; 76(6): 1591-602, 2016 Mar 15.
Article in En | MEDLINE | ID: mdl-26825170
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / ErbB Receptors / Lung Neoplasms / Mutation / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cancer Res Year: 2016 Document type: Article Country of publication:
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Non-Small-Cell Lung / ErbB Receptors / Lung Neoplasms / Mutation / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cancer Res Year: 2016 Document type: Article Country of publication: