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MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma.
Filocamo, Gessica; Brunetti, Mirko; Colaceci, Fabrizio; Sasso, Romina; Tanori, Mirella; Pasquali, Emanuela; Alfonsi, Romina; Mancuso, Mariateresa; Saran, Anna; Lahm, Armin; Di Marcotullio, Lucia; Steinkühler, Christian; Pazzaglia, Simonetta.
Affiliation
  • Filocamo G; Exiris, Rome, Italy. gessica_filocamo@exiris.it simonetta.pazzaglia@enea.it.
  • Brunetti M; Exiris, Rome, Italy.
  • Colaceci F; IRBM Science Park, Pomezia, Rome, Italy.
  • Sasso R; IRBM Science Park, Pomezia, Rome, Italy.
  • Tanori M; Laboratory of Biomedical Technologies, Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (ENEA) CR-Casaccia, Rome, Italy.
  • Pasquali E; Laboratory of Biomedical Technologies, Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (ENEA) CR-Casaccia, Rome, Italy.
  • Alfonsi R; Department of Molecular Medicine, University La Sapienza, Rome, Italy.
  • Mancuso M; Laboratory of Biomedical Technologies, Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (ENEA) CR-Casaccia, Rome, Italy.
  • Saran A; Laboratory of Biomedical Technologies, Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (ENEA) CR-Casaccia, Rome, Italy.
  • Lahm A; Independent expert, Rome, Italy.
  • Di Marcotullio L; Department of Molecular Medicine, University La Sapienza, Rome, Italy.
  • Steinkühler C; Exiris, Rome, Italy. Italfarmaco, Cinisello Balsamo, Milan, Italy.
  • Pazzaglia S; Laboratory of Biomedical Technologies, Agenzia Nazionale per le Nuove Tecnologie, l'Energia e lo Sviluppo Economico Sostenibile (ENEA) CR-Casaccia, Rome, Italy. gessica_filocamo@exiris.it simonetta.pazzaglia@enea.it.
Mol Cancer Ther ; 15(6): 1177-89, 2016 06.
Article in En | MEDLINE | ID: mdl-26960983
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazoles / Carcinoma, Basal Cell / Cerebellar Neoplasms / Hedgehog Proteins / Isoxazoles / Medulloblastoma / Antineoplastic Agents Type of study: Clinical_trials Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2016 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triazoles / Carcinoma, Basal Cell / Cerebellar Neoplasms / Hedgehog Proteins / Isoxazoles / Medulloblastoma / Antineoplastic Agents Type of study: Clinical_trials Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2016 Document type: Article