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Cancer in Drosophila: Imaginal Discs as a Model for Epithelial Tumor Formation.
Herranz, Héctor; Eichenlaub, Teresa; Cohen, Stephen M.
Affiliation
  • Herranz H; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Eichenlaub T; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.
  • Cohen SM; Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark. Electronic address: scohen@sund.ku.dk.
Curr Top Dev Biol ; 116: 181-99, 2016.
Article in En | MEDLINE | ID: mdl-26970620
Cancer genomics has greatly increased our understanding of the complexity of the genetic and epigenetic changes found in human tumors. Understanding the functional relationships among these elements calls for the use of flexible genetic models. We discuss the use of Drosophila models to study cooperation among genetic factors that contribute to disease progression.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drosophila / Epithelial-Mesenchymal Transition / Imaginal Discs / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Curr Top Dev Biol Year: 2016 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drosophila / Epithelial-Mesenchymal Transition / Imaginal Discs / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Curr Top Dev Biol Year: 2016 Document type: Article Affiliation country: Country of publication: