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Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation.
Brook, Matthew; Tomlinson, Gareth H; Miles, Katherine; Smith, Richard W P; Rossi, Adriano G; Hiemstra, Pieter S; van 't Wout, Emily F A; Dean, Jonathan L E; Gray, Nicola K; Lu, Wuyuan; Gray, Mohini.
Affiliation
  • Brook M; Medical Research Council (MRC) Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, Scotland;
  • Tomlinson GH; MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, Scotland;
  • Miles K; MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, Scotland;
  • Smith RW; Medical Research Council (MRC) Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, Scotland;
  • Rossi AG; MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, Scotland;
  • Hiemstra PS; Department of Pulmonology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands;
  • van 't Wout EF; Department of Pulmonology, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands;
  • Dean JL; Kennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, United Kingdom;
  • Gray NK; Medical Research Council (MRC) Centre for Reproductive Health, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, Scotland;
  • Lu W; Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD 21201.
  • Gray M; MRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, Scotland; mohini.gray@ed.ac.uk.
Proc Natl Acad Sci U S A ; 113(16): 4350-5, 2016 Apr 19.
Article in En | MEDLINE | ID: mdl-27044108
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salmonella Infections / Salmonella typhimurium / Protein Biosynthesis / RNA, Messenger / Alpha-Defensins / Macrophages Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Salmonella Infections / Salmonella typhimurium / Protein Biosynthesis / RNA, Messenger / Alpha-Defensins / Macrophages Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2016 Document type: Article Country of publication: