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Acute kidney injury observed during phase 1 clinical trials of a novel xanthine oxidase/URAT1 dual inhibitor PF-06743649.
Dua, Pinky; Gurrell, Rachel; Kirby, Simon; Sudworth, Maria; Loudon, Peter T.
Affiliation
  • Dua P; Pfizer Neuroscience and Pain Research Unit, The Portway Building, Granta Park, Cambridge, CB21 6GS, UK.
  • Gurrell R; Pfizer Neuroscience and Pain Research Unit, The Portway Building, Granta Park, Cambridge, CB21 6GS, UK.
  • Kirby S; Pfizer Neuroscience and Pain Research Unit, The Portway Building, Granta Park, Cambridge, CB21 6GS, UK.
  • Sudworth M; AdClinico Consulting Ltd, Hawks Barn, Dilnot Lane, Acol, CT7 0HW, UK.
  • Loudon PT; Pfizer Neuroscience and Pain Research Unit, The Portway Building, Granta Park, Cambridge, CB21 6GS, UK. peter.t.loudon@pfizer.com.
Clin Rheumatol ; 35(8): 2045-2051, 2016 Aug.
Article in En | MEDLINE | ID: mdl-27094945
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xanthine Oxidase / Gout Suppressants / Organic Anion Transporters / Organic Cation Transport Proteins / Acute Kidney Injury / Gout Type of study: Clinical_trials Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: Clin Rheumatol Year: 2016 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Xanthine Oxidase / Gout Suppressants / Organic Anion Transporters / Organic Cation Transport Proteins / Acute Kidney Injury / Gout Type of study: Clinical_trials Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: America do norte Language: En Journal: Clin Rheumatol Year: 2016 Document type: Article Affiliation country: Country of publication: