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High Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis.
Lanoix, Jean-Philippe; Tasneen, Rokeya; O'Brien, Paul; Sarathy, Jansy; Safi, Hassan; Pinn, Michael; Alland, David; Dartois, Véronique; Nuermberger, Eric.
Affiliation
  • Lanoix JP; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA INSERM U1088, Amiens, France.
  • Tasneen R; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • O'Brien P; Public Health Research Institute and New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, USA.
  • Sarathy J; Public Health Research Institute and New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, USA.
  • Safi H; Department of Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, USA.
  • Pinn M; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Alland D; Department of Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, USA.
  • Dartois V; Public Health Research Institute and New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, New Jersey, USA.
  • Nuermberger E; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA enuermb@jhmi.edu.
Antimicrob Agents Chemother ; 60(7): 4197-205, 2016 07.
Article in En | MEDLINE | ID: mdl-27139472
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazinamide / Tuberculosis / Antitubercular Agents Limits: Animals Language: En Journal: Antimicrob Agents Chemother Year: 2016 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazinamide / Tuberculosis / Antitubercular Agents Limits: Animals Language: En Journal: Antimicrob Agents Chemother Year: 2016 Document type: Article Affiliation country: Country of publication: