Evaluation of the intercept oral specimen collection device with HIV assays versus paired serum/plasma specimens.
J Virol Methods
; 234: 164-8, 2016 08.
Article
in En
| MEDLINE
| ID: mdl-27142112
ABSTRACT
Oral fluid has many advantages over blood-based techniques it is less invasive, eliminates the occupational risk associated with needle stick accidents and collection can be self-administrated. Each individual test is packaged with a corresponding collection device. This study tested the suitability of the Intercept Oral Specimen Collection Device for different HIV diagnostic tests three different rapid HIV tests and two adapted ELISAs, which were evaluated and compared with a gold standard on blood. In addition a total IgG quantification was performed to demonstrate the quality of the specimen. HIV antibodies were detected with a sensitivity of 100%, 99.3%, 98.6%, 100% and 95.7% for, DPP, OraQuick, Aware, Genscreen and Vironostika respectively using the Intercept Collection Device. Respective specificities were 100%, 100%, 99.3%, 97.3% and 100%.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Saliva
/
Specimen Handling
/
AIDS Serodiagnosis
/
HIV Antibodies
/
HIV-1
Type of study:
Diagnostic_studies
/
Evaluation_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
J Virol Methods
Year:
2016
Document type:
Article
Affiliation country: