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Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth.
McIntyre, Alan; Hulikova, Alzbeta; Ledaki, Ioanna; Snell, Cameron; Singleton, Dean; Steers, Graham; Seden, Peter; Jones, Dylan; Bridges, Esther; Wigfield, Simon; Li, Ji-Liang; Russell, Angela; Swietach, Pawel; Harris, Adrian L.
Affiliation
  • McIntyre A; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom. Cancer Biology, Division of Cancer and Stem Cells, University of Nottingham, Nottingham, United Kingdom.
  • Hulikova A; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • Ledaki I; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Snell C; Nuffield Department of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Singleton D; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Steers G; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Seden P; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom. Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
  • Jones D; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Bridges E; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Wigfield S; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Li JL; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Russell A; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom. Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
  • Swietach P; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • Harris AL; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom. aharris.lab@imm.ox.ac.uk.
Cancer Res ; 76(13): 3744-55, 2016 07 01.
Article in En | MEDLINE | ID: mdl-27197160
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bicarbonates / Hypoxia / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2016 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bicarbonates / Hypoxia / Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2016 Document type: Article Affiliation country: