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A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion.
Raimondi, Claudio; Calleja, Veronique; Ferro, Riccardo; Fantin, Alessandro; Riley, Andrew M; Potter, Barry V L; Brennan, Caroline H; Maffucci, Tania; Larijani, Banafshé; Falasca, Marco.
Affiliation
  • Raimondi C; Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Blizard Institute, Inositide Signalling Group, London E1 2AT, UK.
  • Calleja V; Cell Biophysics Laboratory, Cancer Research UK, Lincoln's Inn Fields Laboratories, London Research Institute, London WC2A 3LY, UK.
  • Ferro R; Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Blizard Institute, Inositide Signalling Group, London E1 2AT, UK.
  • Fantin A; UCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.
  • Riley AM; Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.
  • Potter BV; Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.
  • Brennan CH; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT.
  • Maffucci T; Queen Mary University of London, School of Biological and Chemical Sciences, London E1 4NS, UK.
  • Larijani B; Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Blizard Institute, Inositide Signalling Group, London E1 2AT, UK.
  • Falasca M; Cell Biophysics Laboratory, Cancer Research UK, Lincoln's Inn Fields Laboratories, London Research Institute, London WC2A 3LY, UK.
Sci Rep ; 6: 26142, 2016 05 20.
Article in En | MEDLINE | ID: mdl-27199173
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Serine-Threonine Kinases / Enzyme Inhibitors / Phospholipase C gamma / Inositol Phosphates / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Serine-Threonine Kinases / Enzyme Inhibitors / Phospholipase C gamma / Inositol Phosphates / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country: Country of publication: