X chromosome instability associated with familial Turner syndrome.
Clin Genet
; 35(2): 111-5, 1989 Feb.
Article
in En
| MEDLINE
| ID: mdl-2721019
ABSTRACT
A family with two members (two generations) exhibiting Turner syndrome is described. Cytogenetic studies on these individuals showed the presence of multiple X chromosome changes. Evidence is presented to show that the maternally inherited X chromosome is the chromosome involved in the structural alterations observed. The effect of a tendency of the maternal X chromosome to break at specific sites on the development of the Turner phenotype and abnormal karyology is discussed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ring Chromosomes
/
Turner Syndrome
/
X Chromosome
/
Chromosome Aberrations
Type of study:
Risk_factors_studies
Limits:
Child, preschool
/
Female
/
Humans
Language:
En
Journal:
Clin Genet
Year:
1989
Document type:
Article