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Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia.
Richine, B M; Virts, E L; Bowling, J D; Ramdas, B; Mali, R; Naoye, R; Liu, Z; Zhang, Z-Y; Boswell, H S; Kapur, R; Chan, R J.
Affiliation
  • Richine BM; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Virts EL; Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Bowling JD; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Ramdas B; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Mali R; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Naoye R; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Liu Z; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Zhang ZY; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Boswell HS; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Kapur R; Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Chan RJ; Department of Biostatistics, Indiana University Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.
Leukemia ; 30(10): 2094-2097, 2016 10.
Article in En | MEDLINE | ID: mdl-27256702
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Enzyme Inhibitors / Fms-Like Tyrosine Kinase 3 / STAT5 Transcription Factor / Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Syk Kinase Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2016 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Enzyme Inhibitors / Fms-Like Tyrosine Kinase 3 / STAT5 Transcription Factor / Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Syk Kinase Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2016 Document type: Article Affiliation country: Country of publication: