Biogenesis and Function of Transfer RNA-Related Fragments (tRFs).
Trends Biochem Sci
; 41(8): 679-689, 2016 08.
Article
in En
| MEDLINE
| ID: mdl-27263052
ABSTRACT
Noncoding small RNAs arise from the various un-annotated and annotated regions of the genome. When they arise from annotated genes, the noncoding small RNAs are functionally different from the parent genes. This is a brief review of one class of noncoding small RNAs, tRNA-related fragments (tRFs), which are generated from tRNA. tRFs have been suggested to have roles in cell proliferation, priming of viral reverse transcriptases, regulation of gene expression, RNA processing, modulation of the DNA damage response, tumor suppression, and neurodegeneration.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
RNA, Small Untranslated
Limits:
Animals
/
Humans
Language:
En
Journal:
Trends Biochem Sci
Year:
2016
Document type:
Article
Affiliation country: