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A high capacity polymeric micelle of paclitaxel: Implication of high dose drug therapy to safety and in vivo anti-cancer activity.
He, Zhijian; Wan, Xiaomeng; Schulz, Anita; Bludau, Herdis; Dobrovolskaia, Marina A; Stern, Stephan T; Montgomery, Stephanie A; Yuan, Hong; Li, Zibo; Alakhova, Daria; Sokolsky, Marina; Darr, David B; Perou, Charles M; Jordan, Rainer; Luxenhofer, Robert; Kabanov, Alexander V.
Affiliation
  • He Z; Center for Nanotechnology in Drug Delivery and Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC, 27599, USA.
  • Wan X; Center for Nanotechnology in Drug Delivery and Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC, 27599, USA.
  • Schulz A; Professur für Makromolekulare Chemie, Department Chemie, Technische Universität Dresden, Mommsenstr. 4, 01069, Dresden, Germany.
  • Bludau H; Professur für Makromolekulare Chemie, Department Chemie, Technische Universität Dresden, Mommsenstr. 4, 01069, Dresden, Germany.
  • Dobrovolskaia MA; Nanotechnology Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, USA.
  • Stern ST; Nanotechnology Characterization Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, USA.
  • Montgomery SA; Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Yuan H; Department of Radiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Li Z; Department of Radiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.
  • Alakhova D; Center for Nanotechnology in Drug Delivery and Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC, 27599, USA.
  • Sokolsky M; Center for Nanotechnology in Drug Delivery and Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC, 27599, USA.
  • Darr DB; Lineberger Comprehensive Cancer Center, The Animal Study Core, University of North Carolina at Chapel Hill, NC, 27599, USA.
  • Perou CM; Lineberger Comprehensive Cancer Center, The Animal Study Core, University of North Carolina at Chapel Hill, NC, 27599, USA.
  • Jordan R; Professur für Makromolekulare Chemie, Department Chemie, Technische Universität Dresden, Mommsenstr. 4, 01069, Dresden, Germany.
  • Luxenhofer R; Functional Polymer Materials, Chair for Chemical Technology of Materials Synthesis, Julius-Maximilians-Universität Würzburg, Röntgenring 11, 97070, Würzburg, Germany. Electronic address: robert.luxenhofer@uni-wuerzburg.de.
  • Kabanov AV; Center for Nanotechnology in Drug Delivery and Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC, 27599, USA; Laboratory of Chemical Design of Bionanomaterials, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Moscow, 11999
Biomaterials ; 101: 296-309, 2016 09.
Article in En | MEDLINE | ID: mdl-27315213
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxazoles / Drug Carriers / Paclitaxel / Antineoplastic Agents, Phytogenic Limits: Animals / Female / Humans Language: En Journal: Biomaterials Year: 2016 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxazoles / Drug Carriers / Paclitaxel / Antineoplastic Agents, Phytogenic Limits: Animals / Female / Humans Language: En Journal: Biomaterials Year: 2016 Document type: Article Affiliation country: Country of publication: