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Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
Vigorito, Elena; Kuchenbaecker, Karoline B; Beesley, Jonathan; Adlard, Julian; Agnarsson, Bjarni A; Andrulis, Irene L; Arun, Banu K; Barjhoux, Laure; Belotti, Muriel; Benitez, Javier; Berger, Andreas; Bojesen, Anders; Bonanni, Bernardo; Brewer, Carole; Caldes, Trinidad; Caligo, Maria A; Campbell, Ian; Chan, Salina B; Claes, Kathleen B M; Cohn, David E; Cook, Jackie; Daly, Mary B; Damiola, Francesca; Davidson, Rosemarie; Pauw, Antoine de; Delnatte, Capucine; Diez, Orland; Domchek, Susan M; Dumont, Martine; Durda, Katarzyna; Dworniczak, Bernd; Easton, Douglas F; Eccles, Diana; Edwinsdotter Ardnor, Christina; Eeles, Ros; Ejlertsen, Bent; Ellis, Steve; Evans, D Gareth; Feliubadalo, Lidia; Fostira, Florentia; Foulkes, William D; Friedman, Eitan; Frost, Debra; Gaddam, Pragna; Ganz, Patricia A; Garber, Judy; Garcia-Barberan, Vanesa; Gauthier-Villars, Marion; Gehrig, Andrea; Gerdes, Anne-Marie.
Affiliation
  • Vigorito E; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Beesley J; Department of Genetics, QIMR Berghofer Medical Research Institute, Herston Road, Brisbane, Australia, 4029.
  • Adlard J; Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, United Kingdom.
  • Agnarsson BA; Department of Pathology, University Hospital (Landspitali) and University of Iceland School of Medicine, Hringbraut, 101 Reykjavik, Iceland.
  • Andrulis IL; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.
  • Arun BK; Department of Breast Medical Oncology and Clinical Cancer Genetics Program, University Of Texas MD Anderson Cancer Center, 1515 Pressler Street, CBP 5, Houston, TX, United States of America.
  • Barjhoux L; Bâtiment Cheney D, Centre Léon Bérard, 28 rue Laënnec, Lyon, France.
  • Belotti M; Service de Génétique Oncologique, Institut Curie, 26, rue d'Ulm, Paris Cedex 05, France.
  • Benitez J; Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain, and Human Genotyping (CEGEN) Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Berger A; Dept of OB/GYN, Medical University of Vienna, Vienna, Austria.
  • Bojesen A; Department of Clinical Genetics, Vejle Hospital, Kabbeltoft 25, Vejle, Denmark.
  • Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia (IEO), via Ripamonti 435, 20141 Milan, Italy.
  • Brewer C; Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, United Kingdom.
  • Caldes T; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC (El Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Martin Lagos s/n, Madrid, Spain.
  • Caligo MA; Section of Genetic Oncology, Dept. of Laboratory Medicine, University and University Hospital of Pisa, Pisa Italy.
  • Campbell I; Research Division, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett Street, Melbourne, VIC 8006, Australia.
  • Chan SB; 1600 Divisadero Street, C415, San Francisco, CA 94143-1714, United States of America.
  • Claes KB; Center for Medical Genetics, Ghent University, De Pintelaan 185, 9000 Gent, Belgium.
  • Cohn DE; Ohio State University Columbus Cancer Council GYN Oncology, 3651 Ridge Mill Drive, Columbus, OH 43026, United States of America.
  • Cook J; Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, United Kingdom.
  • Daly MB; Department of Clinical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, United States of America.
  • Damiola F; Bâtiment Cheney D, Centre Léon Bérard, 28 rue Laënnec, Lyon, France.
  • Davidson R; Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, United Kingdom.
  • Pauw Ad; Service de Génétique Oncologique, Institut Curie, 26, rue d'Ulm, Paris Cedex 05, France.
  • Delnatte C; Unité d'oncogénétique, ICO-Centre René Gauducheau, Boulevard Jacques Monod, 44805 Nantes Saint Herblain Cedex, France.
  • Diez O; Oncogenetics Group, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), and Universitat Autònoma, Passeig Vall d'Hebron 119-129, Barcelona, Spain.
  • Domchek SM; Department of Medicine, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, United States of America.
  • Dumont M; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, 2705 Laurier Boulevard, Quebec City (Quebec), Canada.
  • Durda K; Department of Genetics and Pathology, Pomeranian Medical University, Polabska 4, Szczecin, Poland.
  • Dworniczak B; Institute of Human Genetics, University of Münster, Münster, Germany.
  • Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
  • Eccles D; University of Southampton Faculty of Medicine, Southampton University Hospitals NHS Trust, Southampton, United Kingdom.
  • Edwinsdotter Ardnor C; Department of Radiation Sciences, Oncology, Umeå University, Umea, Sweden.
  • Eeles R; Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, United Kingdom.
  • Ejlertsen B; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.
  • Ellis S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, United Kingdom.
  • Evans DG; Genomic Medicine, Manchester Academic Health Sciences Centre, Institute of Human Development, Manchester University, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
  • Feliubadalo L; Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Gran Via de l'Hospitalet, 199-203, 08908 L'Hospitalet, Barcelona, Spain.
  • Fostira F; Molecular Diagnostics Laboratory, (INRASTES) Institute of Nuclear and Radiological Sciences and Technology, National Centre for Scientific Research "Demokritos", Patriarchou Gregoriou & Neapoleos str., Aghia Paraskevi, Attiki, Athens, Greece.
  • Foulkes WD; Program in Cancer Genetics, Departments of Human Genetics and Oncology, McGill University, Montreal, Quebec, Canada.
  • Friedman E; The Susanne Levy Gertner Oncogenetics Unit, Institute of Human Genetics, Chaim Sheba Medical Center, Ramat Gan 52621, and Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.
  • Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, United Kingdom.
  • Gaddam P; Clinical Cancer Genetics Laboratory, Memorial Sloane Kettering Cancer Center, New York, NY, United States of America.
  • Ganz PA; UCLA Schools of Medicine and Public Health, Division of Cancer Prevention & Control Research, Jonsson Comprehensive Cancer Center, 650 Charles Young Drive South, Room A2-125 HS, Los Angeles, CA 90095-6900, United States of America.
  • Garber J; Cancer Risk and Prevention Clinic, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, United States of America.
  • Garcia-Barberan V; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC (El Instituto de Investigación Sanitaria del Hospital Clínico San Carlos), Martin Lagos s/n, Madrid, Spain.
  • Gauthier-Villars M; Service de Génétique Oncologique, Institut Curie, 26, rue d'Ulm, Paris Cedex 05, France.
  • Gehrig A; Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Würzburg, Germany.
  • Gerdes AM; Department of Clinical Genetics, Rigshospitalet 4062, Blegdamsvej 9, København Ø, Denmark.
PLoS One ; 11(7): e0158801, 2016.
Article in En | MEDLINE | ID: mdl-27463617
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Chromosomes, Human, Pair 9 / Genes, BRCA1 / Genetic Predisposition to Disease / Genes, BRCA2 / Genetic Carrier Screening Type of study: Etiology_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2016 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Chromosomes, Human, Pair 9 / Genes, BRCA1 / Genetic Predisposition to Disease / Genes, BRCA2 / Genetic Carrier Screening Type of study: Etiology_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2016 Document type: Article Affiliation country: Country of publication: