Heart Transplantation-The Pediatric Cardiac Critical Care Perspective.
Pediatr Crit Care Med
; 17(8 Suppl 1): S171-7, 2016 08.
Article
in En
| MEDLINE
| ID: mdl-27490596
ABSTRACT
OBJECTIVES:
Although there have been tremendous advancements in the care of severe pediatric cardiovascular disease, heart transplantation remains the standard therapy for end-stage heart disease in children. As such, these patients comprise an important and often complex subset of patients in the ICU. The purpose of this article is to review the causes and management of allograft dysfunction and the medications used in the transplant population. DATA SOURCES MEDLINE, PubMed, and Cochrane Database of systemic reviews.CONCLUSIONS:
Pediatric heart transplant recipients represent a complex group of patients that frequently require critical care. Their immunosuppressive medications, while being vital to maintenance of allograft function, are associated with significant short- and long-term complications. Graft dysfunction can occur from a variety of etiologies at different times following transplantation and remains a major limitation to long-term posttransplant survival.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Transplantation, Homologous
/
Heart Transplantation
/
Critical Care
/
Primary Graft Dysfunction
/
Immunosuppressive Agents
Limits:
Child
/
Child, preschool
/
Humans
Language:
En
Journal:
Pediatr Crit Care Med
Journal subject:
PEDIATRIA
/
TERAPIA INTENSIVA
Year:
2016
Document type:
Article