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The selectivity of Marinopyrrole A to induce apoptosis in MCL1high BCL2low expressing myeloma cells is related to its ability to impair protein translation.
Gomez-Bougie, Patricia; Dousset, Christelle; Descamps, Geraldine; Schnitzler, Anne; Audiger, Logan; Tessier, Arnaud; Dubreuil, Didier; Lebreton, Jacques; Pellat-Deceunynck, Catherine; Amiot, Martine.
Affiliation
  • Gomez-Bougie P; CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
  • Dousset C; CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
  • Descamps G; CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
  • Schnitzler A; CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
  • Audiger L; UMR_6230, CHEM-Symbiose, Nantes, France.
  • Tessier A; UMR_6230, CHEM-Symbiose, Nantes, France.
  • Dubreuil D; UMR_6230, CHEM-Symbiose, Nantes, France.
  • Lebreton J; UMR_6230, CHEM-Symbiose, Nantes, France.
  • Pellat-Deceunynck C; CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
  • Amiot M; CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
Br J Haematol ; 180(1): 157-159, 2018 01.
Article in En | MEDLINE | ID: mdl-27523575
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Protein Biosynthesis / Apoptosis / Proto-Oncogene Proteins c-bcl-2 / Myeloid Cell Leukemia Sequence 1 Protein / Multiple Myeloma Limits: Humans Language: En Journal: Br J Haematol Year: 2018 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Protein Biosynthesis / Apoptosis / Proto-Oncogene Proteins c-bcl-2 / Myeloid Cell Leukemia Sequence 1 Protein / Multiple Myeloma Limits: Humans Language: En Journal: Br J Haematol Year: 2018 Document type: Article Affiliation country: Country of publication: