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The Impact of the Hepatocyte-to-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2D6 Substrates.
Rougée, Luc R A; Mohutsky, Michael A; Bedwell, David W; Ruterbories, Kenneth J; Hall, Stephen D.
Affiliation
  • Rougée LR; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana lrougee@lilly.com.
  • Mohutsky MA; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
  • Bedwell DW; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
  • Ruterbories KJ; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
  • Hall SD; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
Drug Metab Dispos ; 44(11): 1819-1827, 2016 11.
Article in En | MEDLINE | ID: mdl-27590024
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Collection: 01-internacional Database: MEDLINE Main subject: Plasma / Cytochrome P-450 CYP2D6 / Hepatocytes / Drug Interactions Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2016 Document type: Article Country of publication:
Search on Google
Add to My VHL
Print
XML
PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Plasma / Cytochrome P-450 CYP2D6 / Hepatocytes / Drug Interactions Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 2016 Document type: Article Country of publication: