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Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors.
Miraglia, Erica; Nylén, Frank; Johansson, Katarina; Arnér, Elias; Cebula, Marcus; Farmand, Susan; Ottosson, Håkan; Strömberg, Roger; Gudmundsson, Gudmundur H; Agerberth, Birgitta; Bergman, Peter.
Affiliation
  • Miraglia E; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Nylén F; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Johansson K; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Arnér E; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Cebula M; Institute of Environmental Medicine, Division of Biochemical Toxicology, Karolinska Institutet, Stockholm, Sweden.
  • Farmand S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
  • Ottosson H; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
  • Strömberg R; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
  • Gudmundsson GH; Biomedical Center, University of Iceland, Reykjavík, Iceland.
  • Agerberth B; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
  • Bergman P; Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Sweden.
Sci Rep ; 6: 33274, 2016 09 16.
Article in En | MEDLINE | ID: mdl-27633343
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Benzamides / STAT3 Transcription Factor / Hypoxia-Inducible Factor 1, alpha Subunit / Cathelicidins / Histone Deacetylase Inhibitors / Job Syndrome Limits: Humans Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Benzamides / STAT3 Transcription Factor / Hypoxia-Inducible Factor 1, alpha Subunit / Cathelicidins / Histone Deacetylase Inhibitors / Job Syndrome Limits: Humans Language: En Journal: Sci Rep Year: 2016 Document type: Article Affiliation country: