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Marsdenia tenacissimae extraction (MTE) inhibits the proliferation and induces the apoptosis of human acute T cell leukemia cells through inactivating PI3K/AKT/mTOR signaling pathway via PTEN enhancement.
Wang, Ying; Chen, Bingyu; Wang, Zhen; Zhang, Wei; Hao, Ke; Chen, Yu; Li, Kaiqiang; Wang, Tongtong; Xie, Yiwei; Huang, Zhihui; Tong, Xiangmin.
Affiliation
  • Wang Y; Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
  • Chen B; Department of Blood Transfusion, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
  • Wang Z; Department of Blood Transfusion, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
  • Zhang W; Department of Blood Transfusion, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
  • Hao K; Clinical Research Institute, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China.
  • Chen Y; Department of Blood Transfusion, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
  • Li K; Clinical Research Institute, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China.
  • Wang T; Department of Blood Transfusion, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
  • Xie Y; Clinical Research Institute, Zhejiang Provincial People's Hospital, Hangzhou, 310014, China.
  • Huang Z; Department of Blood Transfusion, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, 310014, China.
  • Tong X; Key Laboratory of Laboratory Medicine, Ministry of Education, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Oncotarget ; 7(50): 82851-82863, 2016 Dec 13.
Article in En | MEDLINE | ID: mdl-27756877
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Signal Transduction / Apoptosis / Marsdenia / Cell Proliferation / PTEN Phosphohydrolase / Proto-Oncogene Proteins c-akt / Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Phosphatidylinositol 3-Kinase / TOR Serine-Threonine Kinases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncotarget Year: 2016 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plant Extracts / Signal Transduction / Apoptosis / Marsdenia / Cell Proliferation / PTEN Phosphohydrolase / Proto-Oncogene Proteins c-akt / Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Phosphatidylinositol 3-Kinase / TOR Serine-Threonine Kinases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncotarget Year: 2016 Document type: Article Affiliation country: Country of publication: