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Elucidation of the glycosylation steps during biosynthesis of antitumor macrolides PM100117 and PM100118 and engineering for novel derivatives.
Salcedo, Raúl García; Olano, Carlos; Fernández, Rogelio; Braña, Alfredo F; Méndez, Carmen; de la Calle, Fernando; Salas, José A.
Affiliation
  • Salcedo RG; Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Asturias, 33006, Oviedo, Spain.
  • Olano C; Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Asturias, 33006, Oviedo, Spain.
  • Fernández R; Drug Discovery Area, PharmaMar S.A., Avda. de los Reyes, Colmenar Viejo, 128770, Madrid, Spain.
  • Braña AF; Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Asturias, 33006, Oviedo, Spain.
  • Méndez C; Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Asturias, 33006, Oviedo, Spain.
  • de la Calle F; Drug Discovery Area, PharmaMar S.A., Avda. de los Reyes, Colmenar Viejo, 128770, Madrid, Spain.
  • Salas JA; Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Asturias, 33006, Oviedo, Spain. jasalas@uniovi.es.
Microb Cell Fact ; 15(1): 187, 2016 Nov 09.
Article in En | MEDLINE | ID: mdl-27829451
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Engineering / Macrolides / Antineoplastic Agents Limits: Humans Language: En Journal: Microb Cell Fact Journal subject: BIOTECNOLOGIA / MICROBIOLOGIA Year: 2016 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Engineering / Macrolides / Antineoplastic Agents Limits: Humans Language: En Journal: Microb Cell Fact Journal subject: BIOTECNOLOGIA / MICROBIOLOGIA Year: 2016 Document type: Article Affiliation country: