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Cucurbitacin-I induces hypertrophy in H9c2 cardiomyoblasts through activation of autophagy via MEK/ERK1/2 signaling pathway.
Wu, Yao; Chen, Hongying; Li, Ruli; Wang, Xiaoxiao; Li, He; Xin, Juanjuan; Liu, Zhiqiang; Wu, Sisi; Jiang, Wei; Zhu, Ling.
Affiliation
  • Wu Y; School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, PR China; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, PR China.
  • Chen H; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, PR China.
  • Li R; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, PR China.
  • Wang X; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, PR China.
  • Li H; School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, PR China.
  • Xin J; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, PR China.
  • Liu Z; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, PR China.
  • Wu S; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, PR China.
  • Jiang W; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, PR China. Electronic address: wcumsjw@scu.edu.cn.
  • Zhu L; School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, PR China. Electronic address: zhuling529@163.com.
Toxicol Lett ; 264: 87-98, 2016 Dec 15.
Article in En | MEDLINE | ID: mdl-27836799
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Triterpenes / Cardiomegaly / MAP Kinase Kinase Kinases / MAP Kinase Signaling System / Myoblasts, Cardiac Type of study: Prognostic_studies Limits: Humans Language: En Journal: Toxicol Lett Year: 2016 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autophagy / Triterpenes / Cardiomegaly / MAP Kinase Kinase Kinases / MAP Kinase Signaling System / Myoblasts, Cardiac Type of study: Prognostic_studies Limits: Humans Language: En Journal: Toxicol Lett Year: 2016 Document type: Article