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A computationally engineered RAS rheostat reveals RAS-ERK signaling dynamics.
Rose, John C; Huang, Po-Ssu; Camp, Nathan D; Ye, Jordan; Leidal, Andrew M; Goreshnik, Inna; Trevillian, Bridget M; Dickinson, Miles S; Cunningham-Bryant, Daniel; Debnath, Jayanta; Baker, David; Wolf-Yadlin, Alejandro; Maly, Dustin J.
Affiliation
  • Rose JC; Department of Chemistry, University of Washington, Seattle, Washington, USA.
  • Huang PS; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Camp ND; Institute for Protein Design, University of Washington, Seattle, Washington, USA.
  • Ye J; Department of Genome Sciences, University of Washington, Seattle, Washington, USA.
  • Leidal AM; Department of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA.
  • Goreshnik I; Department of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA.
  • Trevillian BM; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Dickinson MS; Department of Chemistry, University of Washington, Seattle, Washington, USA.
  • Cunningham-Bryant D; Department of Chemistry, University of Washington, Seattle, Washington, USA.
  • Debnath J; Department of Chemistry, University of Washington, Seattle, Washington, USA.
  • Baker D; Department of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA.
  • Wolf-Yadlin A; Department of Biochemistry, University of Washington, Seattle, Washington, USA.
  • Maly DJ; Institute for Protein Design, University of Washington, Seattle, Washington, USA.
Nat Chem Biol ; 13(1): 119-126, 2017 Jan.
Article in En | MEDLINE | ID: mdl-27870838
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Engineering / Ras Proteins / MAP Kinase Signaling System / Extracellular Signal-Regulated MAP Kinases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Engineering / Ras Proteins / MAP Kinase Signaling System / Extracellular Signal-Regulated MAP Kinases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2017 Document type: Article Affiliation country: Country of publication: