Response to Anastrozole Treatment in a Case with Peutz-Jeghers Syndrome and a Large Cell Calcifying Sertoli Cell Tumor.
J Clin Res Pediatr Endocrinol
; 9(2): 168-171, 2017 Jun 01.
Article
in En
| MEDLINE
| ID: mdl-27873740
ABSTRACT
Peutz-Jeghers syndrome (PJS) is inherited as an autosomal dominant trait characterized by multiple gastrointestinal hamartomatous polyps, mucocutaneous pigmentation, and an increased risk of neoplasm. Large-cell calcifying Sertoli cell tumor (LCCSCT) is a kind of sex cord-stromal tumor which may co-exist with PJS and which is characterized radiologically by calcification foci within the testes. Surgical treatment options for this tumor range from testis-preserving surgery to radical orchiectomy. Not with standing this invasive approach, recently, there are some case reports demonstrating the efficacy of aromatase inhibitors in avoiding orchiectomy and its associated complications. In this paper, we have presented a LCCSCT case diagnosed in a boy with PJS and his response to anastrozole treatment.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sertoli Cell Tumor
/
Testicular Neoplasms
/
Triazoles
/
Peutz-Jeghers Syndrome
/
Nitriles
Limits:
Child
/
Humans
/
Male
Language:
En
Journal:
J Clin Res Pediatr Endocrinol
Year:
2017
Document type:
Article