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Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease.
Ventham, N T; Kennedy, N A; Adams, A T; Kalla, R; Heath, S; O'Leary, K R; Drummond, H; Wilson, D C; Gut, I G; Nimmo, E R; Satsangi, J.
Affiliation
  • Ventham NT; Gastrointestinal Unit, Centre for Genomics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 6XU, UK.
  • Kennedy NA; Gastrointestinal Unit, Centre for Genomics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 6XU, UK.
  • Adams AT; Gastrointestinal Unit, Centre for Genomics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 6XU, UK.
  • Kalla R; Gastrointestinal Unit, Centre for Genomics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 6XU, UK.
  • Heath S; CNAG-CRG, Centro Nacional de Análisis Genómico, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, Barcelona 08028, Spain.
  • O'Leary KR; Universitat Pompeu Fabra (UPF), Barcelona 08002, Spain.
  • Drummond H; Gastrointestinal Unit, Centre for Genomics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 6XU, UK.
  • Gut IG; Department of Child Life and Health, University of Edinburgh, Edinburgh EH9 1UW, UK.
  • Nimmo ER; CNAG-CRG, Centro Nacional de Análisis Genómico, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, Barcelona 08028, Spain.
  • Satsangi J; Universitat Pompeu Fabra (UPF), Barcelona 08002, Spain.
Nat Commun ; 7: 13507, 2016 11 25.
Article in En | MEDLINE | ID: mdl-27886173
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative / Crohn Disease / DNA Methylation / Genetic Predisposition to Disease / Quantitative Trait Loci Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2016 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative / Crohn Disease / DNA Methylation / Genetic Predisposition to Disease / Quantitative Trait Loci Type of study: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2016 Document type: Article Affiliation country: Country of publication: