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Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.
Li, Jin; Casteels, Tamara; Frogne, Thomas; Ingvorsen, Camilla; Honoré, Christian; Courtney, Monica; Huber, Kilian V M; Schmitner, Nicole; Kimmel, Robin A; Romanov, Roman A; Sturtzel, Caterina; Lardeau, Charles-Hugues; Klughammer, Johanna; Farlik, Matthias; Sdelci, Sara; Vieira, Andhira; Avolio, Fabio; Briand, François; Baburin, Igor; Májek, Peter; Pauler, Florian M; Penz, Thomas; Stukalov, Alexey; Gridling, Manuela; Parapatics, Katja; Barbieux, Charlotte; Berishvili, Ekaterine; Spittler, Andreas; Colinge, Jacques; Bennett, Keiryn L; Hering, Steffen; Sulpice, Thierry; Bock, Christoph; Distel, Martin; Harkany, Tibor; Meyer, Dirk; Superti-Furga, Giulio; Collombat, Patrick; Hecksher-Sørensen, Jacob; Kubicek, Stefan.
Affiliation
  • Li J; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Casteels T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Frogne T; Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark.
  • Ingvorsen C; Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark.
  • Honoré C; Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark.
  • Courtney M; Université Côte d'Azur, INSERM, CNRS, iBV, 06108 Nice, France.
  • Huber KVM; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Schmitner N; Institute of Molecular Biology, Leopold-Franzens-University Innsbruck, Technikerstr. 25, 6020 Innsbruck, Austria.
  • Kimmel RA; Institute of Molecular Biology, Leopold-Franzens-University Innsbruck, Technikerstr. 25, 6020 Innsbruck, Austria.
  • Romanov RA; Department of Molecular Neurosciences, Center for Brain Research, Medical University of Vienna, 1090 Vienna, Austria; Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.
  • Sturtzel C; Children's Cancer Research Institute, Innovative Cancer Models, Zimmermannplatz 10, 1090 Vienna, Austria.
  • Lardeau CH; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria; Christian Doppler Laboratory for Chemical Epigenetics and Antiinfectives, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, 1090 V
  • Klughammer J; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Farlik M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Sdelci S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Vieira A; Université Côte d'Azur, INSERM, CNRS, iBV, 06108 Nice, France.
  • Avolio F; Université Côte d'Azur, INSERM, CNRS, iBV, 06108 Nice, France.
  • Briand F; Physiogenex S.A.S., Prologue Biotech, 516, rue Pierre et Marie Curie, 31670 Labege, France.
  • Baburin I; Institute of Pharmacology and Toxicology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
  • Májek P; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Pauler FM; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Penz T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Stukalov A; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Gridling M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Parapatics K; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Barbieux C; Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals and University of Geneva, 1211 Geneva, Switzerland.
  • Berishvili E; Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals and University of Geneva, 1211 Geneva, Switzerland; Institute of Medical Research, Ilia State University, Tbilisi 0162, Georgia.
  • Spittler A; Core Facility Flow Cytometry and Department of Surgery, Research Laboratories, Medical University of Vienna, 1090 Vienna, Austria.
  • Colinge J; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Bennett KL; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria.
  • Hering S; Institute of Pharmacology and Toxicology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
  • Sulpice T; Physiogenex S.A.S., Prologue Biotech, 516, rue Pierre et Marie Curie, 31670 Labege, France.
  • Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria; Department of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria; Max Planck Institute for Informatics, 66123 Saarbrücken, Germany.
  • Distel M; Children's Cancer Research Institute, Innovative Cancer Models, Zimmermannplatz 10, 1090 Vienna, Austria.
  • Harkany T; Department of Molecular Neurosciences, Center for Brain Research, Medical University of Vienna, 1090 Vienna, Austria; Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.
  • Meyer D; Institute of Molecular Biology, Leopold-Franzens-University Innsbruck, Technikerstr. 25, 6020 Innsbruck, Austria.
  • Superti-Furga G; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria; Center for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.
  • Collombat P; Université Côte d'Azur, INSERM, CNRS, iBV, 06108 Nice, France.
  • Hecksher-Sørensen J; Novo Nordisk A/S, Novo Nordisk Park, DK-2760 Måløv, Denmark.
  • Kubicek S; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Lazarettgasse 14, 1090 Vienna, Austria; Christian Doppler Laboratory for Chemical Epigenetics and Antiinfectives, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, 1090 V
Cell ; 168(1-2): 86-100.e15, 2017 Jan 12.
Article in En | MEDLINE | ID: mdl-27916275
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptors, GABA-A / Artemisinins / Diabetes Mellitus, Type 1 / Disease Models, Animal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptors, GABA-A / Artemisinins / Diabetes Mellitus, Type 1 / Disease Models, Animal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Year: 2017 Document type: Article Affiliation country: Country of publication: