Sound understanding of environmental, health and safety, clinical, and market aspects is imperative to clinical translation of nanomedicines.
Nanotoxicology
; 11(2): 147-149, 2017 03.
Article
in En
| MEDLINE
| ID: mdl-28055261
ABSTRACT
Nanotechnology has transformed materials engineering. However, despite much excitement in the scientific community, translation of nanotechnology-based developments has suffered from significant translational gaps, particularly in the field of biomedicine. Of the many concepts investigated, very few have entered routine clinical application. Safety concerns and associated socioeconomic uncertainties, together with the lack of incentives for technology transfer, are undoubtedly imposing significant hurdles to effective clinical translation of potentially game-changing developments. Commercialisation aspects are only rarely considered in the early stages and in many cases, the market is not identified early on in the process, hence precluding market-oriented development. However, methodologies and in-depth understanding of mechanistic processes existing in the environmental, health and safety (EHS) community could be leveraged to accelerate translation. Here, we discuss the most important stepping stones for (nano)medicine development along with a number of suggestions to facilitate future translation.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Clinical Medicine
/
Nanotechnology
/
Nanomedicine
Type of study:
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Nanotoxicology
Journal subject:
TOXICOLOGIA
Year:
2017
Document type:
Article
Affiliation country: