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A Glu-urea-Lys Ligand-conjugated Lipid Nanoparticle/siRNA System Inhibits Androgen Receptor Expression In Vivo.
Lee, Justin B; Zhang, Kaixin; Tam, Yuen Yi C; Quick, Joslyn; Tam, Ying K; Lin, Paulo Jc; Chen, Sam; Liu, Yan; Nair, Jayaprakash K; Zlatev, Ivan; Rajeev, Kallanthottathil G; Manoharan, Muthiah; Rennie, Paul S; Cullis, Pieter R.
Affiliation
  • Lee JB; Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver, British Columbia, Canada.
  • Zhang K; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
  • Tam YY; Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver, British Columbia, Canada.
  • Quick J; Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver, British Columbia, Canada.
  • Tam YK; Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver, British Columbia, Canada.
  • Lin PJ; Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver, British Columbia, Canada.
  • Chen S; Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver, British Columbia, Canada.
  • Liu Y; Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver, British Columbia, Canada.
  • Nair JK; Department of Drug Discovery, Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Zlatev I; Department of Drug Discovery, Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Rajeev KG; Department of Drug Discovery, Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Manoharan M; Department of Drug Discovery, Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA.
  • Rennie PS; Vancouver Prostate Centre, Vancouver, British Columbia, Canada.
  • Cullis PR; Department of Biochemistry and Molecular Biology at the University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: pieterc@mail.ubc.ca.
Mol Ther Nucleic Acids ; 5: e348, 2016.
Article in En | MEDLINE | ID: mdl-28131285
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Mol Ther Nucleic Acids Year: 2016 Document type: Article Affiliation country:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Mol Ther Nucleic Acids Year: 2016 Document type: Article Affiliation country: