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PLCG2 C2 domain mutations co-occur with BTK and PLCG2 resistance mutations in chronic lymphocytic leukemia undergoing ibrutinib treatment.
Jones, D; Woyach, J A; Zhao, W; Caruthers, S; Tu, H; Coleman, J; Byrd, J C; Johnson, A J; Lozanski, G.
Affiliation
  • Jones D; Department of Pathology, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
  • Woyach JA; Division of Hematology, Department of Internal Medicine, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
  • Zhao W; Department of Pathology, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
  • Caruthers S; James Polaris Molecular Laboratory, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
  • Tu H; James Polaris Molecular Laboratory, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
  • Coleman J; Department of Pathology, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
  • Byrd JC; Division of Hematology, Department of Internal Medicine, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
  • Johnson AJ; Division of Hematology, Department of Internal Medicine, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
  • Lozanski G; Department of Pathology, The Ohio State University and James Cancer Hospital, Columbus, OH, USA.
Leukemia ; 31(7): 1645-1647, 2017 07.
Article in En | MEDLINE | ID: mdl-28366935
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrimidines / Protein-Tyrosine Kinases / Leukemia, Lymphocytic, Chronic, B-Cell / Drug Resistance, Neoplasm / Protein Kinase Inhibitors / Phospholipase C gamma / C2 Domains / Mutation Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrimidines / Protein-Tyrosine Kinases / Leukemia, Lymphocytic, Chronic, B-Cell / Drug Resistance, Neoplasm / Protein Kinase Inhibitors / Phospholipase C gamma / C2 Domains / Mutation Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Country of publication: