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Functional validation of the oncogenic cooperativity and targeting potential of tuberous sclerosis mutation in medulloblastoma using a MYC-amplified model cell line.
Henderson, Jacob J; Wagner, Jacob P; Hofmann, Nicolle E; Eide, Christopher A; Cho, Yoon-Jae; Druker, Brian J; Davare, Monika A.
Affiliation
  • Henderson JJ; Department of Pediatrics, Doernbecher Children's Hospital, Papé Pediatric Research Institute, Oregon Health and Science University, Portland, Oregon.
  • Wagner JP; Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon.
  • Hofmann NE; Department of Pediatrics, Doernbecher Children's Hospital, Papé Pediatric Research Institute, Oregon Health and Science University, Portland, Oregon.
  • Eide CA; Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon.
  • Cho YJ; Howard Hughes Medical Institute, Portland, Oregon.
  • Druker BJ; Department of Pediatrics, Doernbecher Children's Hospital, Papé Pediatric Research Institute, Oregon Health and Science University, Portland, Oregon.
  • Davare MA; Department of Pediatric Neurology, Doernbecher Children's Hospital, Oregon Health and Science University, Portland, Oregon.
Pediatr Blood Cancer ; 64(10)2017 Oct.
Article in En | MEDLINE | ID: mdl-28409891
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Gene Amplification / Proto-Oncogene Proteins c-myc / Mutation, Missense / Tumor Suppressor Proteins / Medulloblastoma Limits: Humans Language: En Journal: Pediatr Blood Cancer Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2017 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Gene Amplification / Proto-Oncogene Proteins c-myc / Mutation, Missense / Tumor Suppressor Proteins / Medulloblastoma Limits: Humans Language: En Journal: Pediatr Blood Cancer Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2017 Document type: Article Country of publication: