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Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo.
Allweiss, Lena; Volz, Tassilo; Giersch, Katja; Kah, Janine; Raffa, Giuseppina; Petersen, Joerg; Lohse, Ansgar W; Beninati, Concetta; Pollicino, Teresa; Urban, Stephan; Lütgehetmann, Marc; Dandri, Maura.
Affiliation
  • Allweiss L; Department of Medicine, Center for Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Volz T; Department of Medicine, Center for Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Giersch K; Department of Medicine, Center for Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Kah J; Department of Medicine, Center for Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Raffa G; Department of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
  • Petersen J; IFI Institute for Interdisciplinary Medicine at Asklepios Clinic St. Georg, Hamburg, Germany.
  • Lohse AW; Department of Medicine, Center for Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Beninati C; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel and Heidelberg Partner Sites, Hamburg, Germany.
  • Pollicino T; Department of Human Pathology, University Hospital of Messina, Messina, Italy.
  • Urban S; Department of Clinical and Experimental Medicine, University Hospital of Messina, Messina, Italy.
  • Lütgehetmann M; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel and Heidelberg Partner Sites, Hamburg, Germany.
  • Dandri M; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany.
Gut ; 67(3): 542-552, 2018 03.
Article in En | MEDLINE | ID: mdl-28428345
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Circular / DNA, Viral / Hepatitis B virus / Hepatitis B, Chronic / Hepatocytes / Cell Proliferation Limits: Animals / Humans Language: En Journal: Gut Year: 2018 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Circular / DNA, Viral / Hepatitis B virus / Hepatitis B, Chronic / Hepatocytes / Cell Proliferation Limits: Animals / Humans Language: En Journal: Gut Year: 2018 Document type: Article Affiliation country: