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Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency.
Agadjanyan, Michael G; Zagorski, Karen; Petrushina, Irina; Davtyan, Hayk; Kazarian, Konstantin; Antonenko, Maxim; Davis, Joy; Bon, Charles; Blurton-Jones, Mathew; Cribbs, David H; Ghochikyan, Anahit.
Affiliation
  • Agadjanyan MG; Department of Molecular Immunology, Institute for Molecular Medicine, 16371 Gothard St, Huntington Beach, CA, 92647, USA. magadjanyan@immed.org.
  • Zagorski K; The Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, 92697, USA. magadjanyan@immed.org.
  • Petrushina I; Department of Molecular Immunology, Institute for Molecular Medicine, 16371 Gothard St, Huntington Beach, CA, 92647, USA.
  • Davtyan H; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE, 68198-6025, USA.
  • Kazarian K; The Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, 92697, USA.
  • Antonenko M; Department of Molecular Immunology, Institute for Molecular Medicine, 16371 Gothard St, Huntington Beach, CA, 92647, USA.
  • Davis J; Department of Molecular Immunology, Institute for Molecular Medicine, 16371 Gothard St, Huntington Beach, CA, 92647, USA.
  • Bon C; Department of Molecular Immunology, Institute for Molecular Medicine, 16371 Gothard St, Huntington Beach, CA, 92647, USA.
  • Blurton-Jones M; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, 92697, USA.
  • Cribbs DH; Biostudy Solutions LLC, Wilmington, NC, USA.
  • Ghochikyan A; The Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, 92697, USA.
Mol Neurodegener ; 12(1): 33, 2017 05 05.
Article in En | MEDLINE | ID: mdl-28472993

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Tau Proteins / Tauopathies / Antibodies, Monoclonal, Humanized Limits: Animals / Humans Language: En Journal: Mol Neurodegener Year: 2017 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Tau Proteins / Tauopathies / Antibodies, Monoclonal, Humanized Limits: Animals / Humans Language: En Journal: Mol Neurodegener Year: 2017 Document type: Article Affiliation country: Country of publication: