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Rhodium metalloinsertor binding generates a lesion with selective cytotoxicity for mismatch repair-deficient cells.
Bailis, Julie M; Weidmann, Alyson G; Mariano, Natalie F; Barton, Jacqueline K.
Affiliation
  • Bailis JM; Department of Oncology Research, Amgen, Inc., South San Francisco, CA 94080; jbailis@amgen.com jkbarton@caltech.edu.
  • Weidmann AG; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
  • Mariano NF; Department of Oncology Research, Amgen, Inc., South San Francisco, CA 94080.
  • Barton JK; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125 jbailis@amgen.com jkbarton@caltech.edu.
Proc Natl Acad Sci U S A ; 114(27): 6948-6953, 2017 07 03.
Article in En | MEDLINE | ID: mdl-28634291
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhodium / DNA Damage / DNA / Cell Cycle / Cytotoxins / DNA Mismatch Repair / Coordination Complexes Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2017 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhodium / DNA Damage / DNA / Cell Cycle / Cytotoxins / DNA Mismatch Repair / Coordination Complexes Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2017 Document type: Article Country of publication: