Does Sugammadex Administration Affect Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy: A Prospective, Double-Blind, Randomized Study.
Surg Laparosc Endosc Percutan Tech
; 27(4): 237-240, 2017 Aug.
Article
in En
| MEDLINE
| ID: mdl-28731951
ABSTRACT
BACKGROUND:
The aim of this study is to assess the effect of sugammadex on postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy.METHODS:
Eighty patients who were scheduled for elective laparoscopic cholecystectomy surgery were enrolled in this prospective study. Patients were randomly assigned to neostigmine (group N) or sugammadex (group S) for neuromuscular antagonism at the end of anesthesia. The incidence of PONV and antiemetic consumption were recorded.RESULTS:
Nausea and vomiting were observed in 60% of the patients given sugammadex and 77.5% given neostigmine during the initial 24 hours postoperatively. The incidence of nausea and the need for rescue antiemetic were lower in group S than group N during all time intervals but there were no significant differences between the groups.CONCLUSIONS:
Sugammadex seems to be effective in decreasing the incidence of PONV, severity of nausea, number of patients who suffered from nausea and vomiting, and need for rescue antiemetic, although there were no significant differences.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cholecystectomy, Laparoscopic
/
Postoperative Nausea and Vomiting
/
Gamma-Cyclodextrins
Type of study:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Surg Laparosc Endosc Percutan Tech
Journal subject:
DIAGNOSTICO POR IMAGEM
/
GASTROENTEROLOGIA
Year:
2017
Document type:
Article
Affiliation country: