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Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats.
Mahmoud, Ayman M; Hozayen, Walaa G; Ramadan, Shimaa M.
Affiliation
  • Mahmoud AM; Physiology Division, Department of Zoology, Faculty of Science, Beni-Suef University, Egypt. Electronic address: ayman.mahmoud@science.bsu.edu.eg.
  • Hozayen WG; Biochemistry Division, Chemistry Department, Faculty of Science, Beni-Suef University, Egypt; Biotechnology and Life Sciences Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Egypt.
  • Ramadan SM; Biochemistry Division, Chemistry Department, Faculty of Science, Beni-Suef University, Egypt.
Biomed Pharmacother ; 94: 280-291, 2017 Oct.
Article in En | MEDLINE | ID: mdl-28763751
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Berberine / Apoptosis / Oxidative Stress / PPAR gamma / NF-E2-Related Factor 2 / Chemical and Drug Induced Liver Injury / Heme Oxygenase (Decyclizing) Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2017 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Berberine / Apoptosis / Oxidative Stress / PPAR gamma / NF-E2-Related Factor 2 / Chemical and Drug Induced Liver Injury / Heme Oxygenase (Decyclizing) Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2017 Document type: Article Country of publication: