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Lentiviral vector-mediated shRNAs targeting a functional isoform of the leptin receptor (Ob-Rb) inhibit cartilage degeneration in a rat model of osteoarthritis.
Deng, S L; Zhu, J; Huang, Q; Fu, W L; Li, Q; Chen, G; Tang, X; Li, J.
Affiliation
  • Deng SL; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Zhu J; Respiratory and Thoracic Surgery Ward, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Huang Q; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Fu WL; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Li Q; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Chen G; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
  • Tang X; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China. Electronic address: tangxin9388@163.com.
  • Li J; Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Osteoarthritis Cartilage ; 25(11): 1912-1921, 2017 11.
Article in En | MEDLINE | ID: mdl-28823646
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cartilage, Articular / Chondrocytes / Osteoarthritis, Knee / RNA, Small Interfering / Receptors, Leptin Type of study: Prognostic_studies Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2017 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cartilage, Articular / Chondrocytes / Osteoarthritis, Knee / RNA, Small Interfering / Receptors, Leptin Type of study: Prognostic_studies Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2017 Document type: Article Affiliation country: Country of publication: