Sarcoidosis and Wound Healing After Cellulitis of the Lower Limb: Is Methotrexate Responsible for Skin Graft Failure?
Wounds
; 29(8): 229-230, 2017 Aug.
Article
in En
| MEDLINE
| ID: mdl-28862976
ABSTRACT
The authors report the case of a 53-year-old man with diffuse cutaneous and mediastinal pulmonary sarcoidosis and well-controlled steroid-induced diabetes. He was hospitalized for cellulitis of his left leg. His standard treatment for sarcoidosis consisted of prednisone and methotrexate. Prednisone was stopped at his admission. He received antibiotics for 4 weeks to treat the cellulitis. In parallel, the leg wound was treated with daily silver sulfadiazine applications until necrosis removal, then by skin autografting. Four successive procedures were performed, but all failed despite lack of surgical problem or local infection. Methotrexate was stopped after the fourth grafting procedure failed; the fifth, and final, autografting procedure was successfully performed.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Wound Healing
/
Cellulitis
/
Methotrexate
/
Sarcoidosis, Pulmonary
/
Dermatologic Agents
/
Graft Rejection
Type of study:
Etiology_studies
Limits:
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Wounds
Year:
2017
Document type:
Article
Affiliation country: