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Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.
Obeso, J A; Stamelou, M; Goetz, C G; Poewe, W; Lang, A E; Weintraub, D; Burn, D; Halliday, G M; Bezard, E; Przedborski, S; Lehericy, S; Brooks, D J; Rothwell, J C; Hallett, M; DeLong, M R; Marras, C; Tanner, C M; Ross, G W; Langston, J W; Klein, C; Bonifati, V; Jankovic, J; Lozano, A M; Deuschl, G; Bergman, H; Tolosa, E; Rodriguez-Violante, M; Fahn, S; Postuma, R B; Berg, D; Marek, K; Standaert, D G; Surmeier, D J; Olanow, C W; Kordower, J H; Calabresi, P; Schapira, A H V; Stoessl, A J.
Affiliation
  • Obeso JA; HM CINAC, Hospital Universitario HM Puerta del Sur, Mostoles, Madrid, Spain.
  • Stamelou M; Universidad CEU San Pablo, Madrid, Spain.
  • Goetz CG; CIBERNED, Madrid, Spain.
  • Poewe W; Department of Neurology, Philipps University, Marburg, Germany.
  • Lang AE; Parkinson's Disease and Movement Disorders Department, HYGEIA Hospital and Attikon Hospital, University of Athens, Athens, Greece.
  • Weintraub D; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.
  • Burn D; Department of Neurology, Medical University Innsbruck, Innsbruck, Austria.
  • Halliday GM; Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J Safra Program in Parkinson's Disease, Toronto Western Hospital, Toronto, Canada.
  • Bezard E; Department of Medicine, University of Toronto, Toronto, Canada.
  • Przedborski S; Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Lehericy S; Parkinson's Disease and Mental Illness Research, Education and Clinical Centers (PADRECC and MIRECC), Corporal Michael J. Crescenz Veteran's Affairs Medical Center, Philadelphia, Pennsylvania, USA.
  • Brooks DJ; Medical Sciences, Newcastle University, Newcastle, UK.
  • Rothwell JC; Brain and Mind Centre, Sydney Medical School, The University of Sydney, Sydney, Australia.
  • Hallett M; School of Medical Sciences, University of New South Wales and Neuroscience Research Australia, Sydney, Australia.
  • DeLong MR; Université de Bordeaux, Institut des Maladies Neurodégénératives, Centre National de la Recherche Scientifique Unité Mixte de Recherche 5293, Institut des Maladies Neurodégénératives, Bordeaux, France.
  • Marras C; China Academy of Medical Sciences, Institute of Lab Animal Sciences, Beijing, China.
  • Tanner CM; Departments of Neurology, Pathology, and Cell Biology, the Center for Motor Neuron Biology and Disease, Columbia University, New York, New York, USA.
  • Ross GW; Columbia Translational Neuroscience Initiative, Columbia University, New York, New York, USA.
  • Langston JW; Institut du Cerveau et de la Moelle épinière - ICM, Centre de NeuroImagerie de Recherche - CENIR, Sorbonne Universités, UPMC Univ Paris 06, Inserm U1127, CNRS UMR 7225, Paris, France.
  • Klein C; Groupe Hospitalier Pitié-Salpêtrière, Paris, France.
  • Bonifati V; Clinical Sciences Department, Newcastle University, Newcastle, UK.
  • Jankovic J; Department of Nuclear Medicine, Aarhus University, Aarhus, Denmark.
  • Lozano AM; Human Neurophysiology, Sobell Department, UCL Institute of Neurology, London, UK.
  • Deuschl G; Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
  • Bergman H; Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
  • Tolosa E; Morton and Gloria Shulman Movement Disorders Centre and the Edmond J Safra Program in Parkinson's disease, Toronto Western Hospital, University of Toronto, Toronto, Canada.
  • Rodriguez-Violante M; Movement Disorders and Neuromodulation Center, Department of Neurology, University of California-San Francisco, San Francisco, California, USA.
  • Fahn S; Parkinson's Disease Research, Education and Clinical Center, San Francisco Veterans Affairs Medical Center, San Francisco, California, USA.
  • Postuma RB; Veterans Affairs Pacific Islands Health Care System, Honolulu, Hawaii, USA.
  • Berg D; Parkinson's Institute, Sunnyvale, California, USA.
  • Marek K; Institute of Neurogenetics, University of Luebeck, Luebeck, Germany.
  • Standaert DG; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Surmeier DJ; Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, Texas, USA.
  • Olanow CW; Department of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Canada.
  • Kordower JH; Department of Neurology, Universitätsklinikum Schleswig-Holstein, Christian Albrechts University Kiel, Kiel, Germany.
  • Calabresi P; Department of Medical Neurobiology, Institute of Medical Research Israel-Canada, Jerusalem, Israel.
  • Schapira AHV; Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, Jerusalem, Israel.
  • Stoessl AJ; Department of Neurosurgery, Hadassah University Hospital, Jerusalem, Israel.
Mov Disord ; 32(9): 1264-1310, 2017 Sep.
Article in En | MEDLINE | ID: mdl-28887905
ABSTRACT
This article reviews and summarizes 200 years of Parkinson's disease. It comprises a relevant history of Dr. James Parkinson's himself and what he described accurately and what he missed from today's perspective. Parkinson's disease today is understood as a multietiological condition with uncertain etiopathogenesis. Many advances have occurred regarding pathophysiology and symptomatic treatments, but critically important issues are still pending resolution. Among the latter, the need to modify disease progression is undoubtedly a priority. In sum, this multiple-author article, prepared to commemorate the bicentenary of the shaking palsy, provides a historical state-of-the-art account of what has been achieved, the current situation, and how to progress toward resolving Parkinson's disease. © 2017 International Parkinson and Movement Disorder Society.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease Limits: Humans Language: En Journal: Mov Disord Journal subject: NEUROLOGIA Year: 2017 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease Limits: Humans Language: En Journal: Mov Disord Journal subject: NEUROLOGIA Year: 2017 Document type: Article Affiliation country: